Ines Sastre's career started at the age of 12, when she was selected for a fast-food commercial with McDonalds. Her first movie appearance occurred in 1987 in El dorado by Carlos Saura. In 1989, she was awarded the look of the year by the Elite Model Agency group. At that point in her life she was offered to continue in the modelling business but she chose to continue her studies instead.

She studied at The Sorbonne in Paris, and in addition to Spanish, speaks French, English and Italian fluently. In 1996, Sastre succeeded Isabella Rossellini as Lancôme's spokesmodel for its perfume, Trésor.

In 1997, before playing the role of Francesca Babini in Italian director Pupi Avati's movie Il testimone dello sposo, she became the Beauté Naturelle for having won the Prix de la mode in Paris' Fashion Awards. The following years saw her work with UNESCO and take part in a multitude of fashion design shows, and also taking part in numerous ads.

In 2000, Sastre achieved popularity in Italy as a presenter with Fabio Fazio at the Italian Music Festival di San Remo.

--Wikipedia