The title character is Peter Griffin, an inept blue-collar worker head of a middle class family frequently beset by the consequences of his foolish antics. Family Guy's brand of humor is notable for the (usually) brief, frequently nonsensical cutaways and flashbacks to various points in history, geography, and reality involving the characters and their ludicrous actions.
MacFarlane also serves as a writer on the show, and voices many of the characters. Other voice actors include That '70s Show star Mila Kunis, actor Seth Green, MADtv star Alex Borstein, and comedic actor Patrick Warburton.
--Wikipedia